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. 2009 Aug 27;4(8):e6796. doi: 10.1371/journal.pone.0006796

Figure 7. Partial conservation of Wy14643-induced gene regulation between mouse and human hepatocytes.

Figure 7

Heat map illustrating the relative induction of the top 50 of upregulated genes in response to 6 h Wy14643 treatment in mouse hepatocytes. All genes were significantly changed (P<0.05) and were ranked based on mean fold-change (MFC). Expression levels in the DMSO-treated cells were set at 1. Relative changes in expression of the corresponding human orthologs in human hepatocytes are shown in parallel.