Skip to main content
. 2009 Aug 26;4(8):e6764. doi: 10.1371/journal.pone.0006764

Figure 2. Identification of Statistically Significant Genes.

Figure 2

Scatter-plots of signal intensity comparisons between GFP siRNA and UCH L1 siRNA. Each point represents a gene and the data: red points represent genes expressed to a higher degree in UCH L1 siRNA along the y-axis and green points represents genes expressed to a lower degree in UCH L1 siRNA along the x-axis. Grey squares represent genes changed less than 1.5 fold or with a p-value that failed to reach 0.05 (A). Unsupervised clustering of samples by principal component analysis (B). Each dot represents a gene on the plot. The distance between any pair of the samples is a function of relative similarity between the two samples. Venn diagram analyses (C) of gene list common in both cell types. The numbers in the center represent genes that are either up-regulated (left) or down-regulated genes (right) in common for both 293T and KR4 cells, whereas the numbers within the left circle represent genes regulated in KR4 independently of 293T and vice versa.