Table 1.
| |||||||
---|---|---|---|---|---|---|---|
Entry | Thiol | Donor | Disulfide (% yield) | Solvent | Temp (°C) | PR3 | Product (% yield) |
1 | Me(CH2)7SH | PhMe | 110 | PPh3 | |||
17 | 18 (72) | 19 (71) | |||||
2 | PhSH | PhMe | 110 | PPh3 | |||
17 | 20 (95) | 21 (69) | |||||
3 | PhSH | C6D6 | rt | P(NEt2)3 | |||
22 | 23 (73) | 24 (80) | |||||
4 | CD3OD | rt | P(NEt2)3 | ||||
25 | 26 | 27 (77) | 28 (73) |