Fig. 3.
FR-2 shuttle box deficits are pharmacologically dissociable. The bold line represents the period of drug administration after IS. TS test session. Data are expressed as group mean escape failures±SEM (n=7–8 per group) a DMI treatment (6 days, 24 mg/kg/day) resulted in significantly fewer escape failures than SAL and FLX (5 mg/kg/day) treatment at the first test session. b DMI treatment resulted in improved escape performance at each test session compared to both SAL and FLX treatment except test session 3 where DMI was not significantly different from FLX. A linear trend for improved escape performance across test sessions was observed in the FLX, but not in DMI- or SAL-treated animals. *p<0.01 compared to SAL, ‡p<0.01 compared to FLX, ptrend<0.001