TABLE 2.

Count and Rates of Invasive Squamous Cell^* Anal Cancer by Sex andby Age, Race, Ethnicity, and Region—US, 1998 to 2003^†

	Male				Female
	Count	Rate‡	95% CI	RR	Count	Rate	95% CI	RR
Total	6497	1.00	0.98–1.03		11,608	1.51	1.48–1.54
Age, y
<50	2185	0.44	0.42–0.45	1.00	2531	0.50	0.48–0.52	1.00
50–64	2098	2.03	1.95–2.12	4.66§	3823	3.46	3.35–3.57	6.97§
≥65	2214	3.01	2.88–3.14	6.90§	5254	5.01	4.88–5.15	10.09§
Race
White	5559	0.99	0.96–1.01	1.00	10,436	1.58	1.54–1.61	1.00
Black	743	1.21	1.12–1.31	1.23§	911	1.28	1.20–1.37	0.81§
API	45	0.20	0.14–0.27	0.20§	112	0.43	0.36–0.52	0.28§
Ethnicity
Non-Hispanic	6067	1.02	1.00–1.05	1.00	10,777	1.53	1.50–1.56	1.00
Hispanic‖	430	0.78	0.70–0.86	0.76§	831	1.50	1.40–1.61	0.98
Region
Northeast	1545	1.03	0.98–1.08	1.00	2543	1.38	1.33–1.44	1.00
Midwest	1438	0.82	0.78–0.86	0.80§	2886	1.39	1.34–1.44	1.01
South	1907	1.08	1.03–1.13	1.05	3588	1.72	1.66–1.77	1.24§
West	1607	1.10	1.05–1.16	1.07	2591	1.57	1.51–1.63	1.14§

95% CI indicates 95% confidence interval; RR, rate ratio; API, Asian/Pacific Islander.

^*Includes squamous cell carcinoma of the anus, anal canal, and rectum and the squamous cell variants classified as transitional cell, basaloid, and cloacogenic.

^†Data are from 39 population-based cancer registries that participate in the National Program of Cancer Registries and/or the National Cancer Institute’s Surveillance, Epidemiology, and End Results program and meet the high-quality data criteria.¹⁰ These registries cover 83% of the US population.

^‡Rates are per 100,000 population and are age-adjusted to the 2000 US standard population (19 age groups, Census P25-1130).

^§Significant at P ≤.05.

^‖Hispanic origin is not mutually exclusive of race categories (white, black, API).