Table 1.
Role of gliotoxin in pathobiology of Aspergillus fumigatus studied in five laboratories.
| Strain background |
Gene deleted | Mouse strains | Immunosuppressive regimen | Inoculation method |
Virulence | Reference |
|---|---|---|---|---|---|---|
| Af293 | gliP | ICR | Cyclophosphamide+Cortisone | Inhalation | No effect | [7] |
| Af293 | gliP | BALB/C | Cyclophosphamide+Cortisone | Inhalation | No effect | [4] |
| Af293 | gliP | BALB/C | Cortisone | Inhalation | Attenuated | [4] |
| CEA10 | gliP | BALB/C | Cyclophosphamide+Cortisone | Intranasal | No effect | [5] |
| B-5233 | gliP | BALB/C | Cortisone | Intranasal | Attenuated | [6] |
| B-5233 | gliP | 129/Sv | Cortisone | Intranasal | Attenuated | [6] |
| Af293 | gliZ | ICR | Cyclophosphamide+Cortisone | Intranasal | No effect | [8] |