Table 1. Baseline Characteristics of Study Participants.
Characteristic | Men (N=235) |
Women (N=360) |
---|---|---|
Clinical Data | ||
Age, yrs | 54±9 | 55±9 |
Body mass index, kg/m2 | 27.1±3.8 | 25.5±4.9 |
Systolic blood pressure, mm Hg | 119±10 | 115±13 |
Diastolic blood pressure, mm Hg | 75±7 | 70±8 |
Optimal BP, % | 48.9 | 59.7 |
Normal BP % | 27.7 | 21.7 |
Diabetes, % | 5.5 | 2.2 |
Current cigarette smoking, % | 14.0 | 18.1 |
Weight change, % | 0.7±5.3 | 1.1±6.5 |
Sex-specific LVID and LVWT distributions, % | ||
LVID and LVWT <50th percentile | 73.6 | 72.2 |
LVID or LVWT >90th percentile | 26.4 | 27.8 |
Matrix remodeling markers, ng/mL | ||
TIMP-1, median IQR | 776 (154) | 734 (148) |
PIIINP, median IQR | 3.08 (1.47) | 3.03 (1.55) |
MMP-9, % detectable | 17.5 | 17.3 |
All values are mean ± standard deviation or otherwise indicated
Optimal blood pressure, systolic <120 mm Hg and diastolic <80 mm Hg; normal blood pressure, systolic 120-129 mm Hg or diastolic 80-84 mm Hg; high normal blood pressure, systolic 130-139 mm Hg or diastolic 85-89 mm Hg.
TIMP-1: tissue inhibitor of metalloprotein-1; MMP-9: matrix metalloprotein-9; PIIINP: procollagen III N terminal peptide; LVID: Left ventricular internal dimension; LVWT: left ventricular wall thickness