TABLE 1.

Binding data for β₃AR agonists in CHOK1 cells transfected with rat and human β₃AR

Ligand	Rat β3AR			Human β3AR
	Log IC50 ± S.E.M.	Ki	n	Log IC50 ± S.E.M.	Ki	n
		M			M
Isoproterenol	–4.15 ± 0.506	7.09 × 10–5	9	–5.34 ± 0.302	4.58 × 10–6	7
BRL37344	–5.60 ± 0.281	2.51 × 10–6	7	–6.16 ± 0.211	6.95 × 10–7	9
TAK-677	–6.09 ± 0.273	8.17 × 10–7	8	–6.89 ± 0.449	1.30 × 10–7	8
FK175	–4.97 ± 0.350	1.07 × 10–5	6	–6.35 ± 0.215	4.46 × 10–7	8

n, number of experiments