Table 1. Genes of P. aeruginosa PAO1 with increased expression in cells overexpressing the vreI ECF sigma factor.
| ORFa | Gene | Function or classb | Fold change VreI vs WT |
| PA0149 | ECF sigma factor | 7.4 | |
| PA0532 | HUU | 16.8 | |
| PA0674 | vreA | N-terminal half similar to TonB-dependent transducers | 10.3 |
| PA0675 | vreI | ECF sigma factor | >100 |
| PA0676 | vreR | Transmembrane sensor (sigma factor regulator) | >100 |
| PA0678 | hxcU | Type II secretion system protein | 5.6 |
| PA0679 | hxcP | Type II secretion system protein | 9.3 |
| PA0682 | hxcX | Type II secretion system protein | 8.5 |
| PA0683 | hxcY | Type II secretion system protein | 18.6 |
| PA0684 | hxcZ | Type II secretion system protein | 3.4 |
| PA0685 | hxcQ | Type II secretion system protein | 4.4 |
| PA0688 | Low molecular weight alkaline phosphatase (PhoA) | 5.2 | |
| PA0690 | tpsA | Large exoprotein secreted by the TPS pathway | 7.9 |
| PA0691 | Similar to transposase | 16.2 | |
| PA0692 | tpsB | Outer membrane transporter of the TPS pathway | 17.8 |
| PA0693 | exbB2 | Cytoplasmic membrane protein ExbB2 | 5.0 |
| PA0694 | exbD2 | Cytoplasmic membrane protein ExbD2 | 3.2 |
| PA0696 | HUU; predicted signal peptide | 17.0 | |
| PA0697 | HUU; predicted signal peptide and a DNA binding motif | 25.9 | |
| PA0698 | HUU | 3.2 | |
| PA0699 | Peptidyl-prolyl cis-trans isomerase, PpiC-type | 2.6 | |
| PA0716 | Putative ATP-binding component of ABC transport system | 3.9 | |
| PA1652 | HUU; membrane protein | 4.9 | |
| PA2349 | 54% similar to putative lipoprotein YaeC of E. coli | 3.1 | |
| PA2384 | Probable Fur, Fe2+/Zn2+ uptake regulation protein | 3.1 | |
| PA2404 | HUU; membrane protein | 3.0 | |
| PA2784 | HUU; membrane protein | 2.5 | |
| PA4192 | Probable ATP-binding component of polar amino acid ABC transport system | 9.7 | |
| PA5403 | Probable transcriptional regulator | 10.3 | |
| PA5405 | HUU; Putative lipoprotein export signal (predicted by LipoP) | 5.8 |
a
PA number attributed in the P. aeruginosa genome annotation project (http://www.pseudomonas.com) [52].
b
The functions of the encoded proteins are indicated according to the PAO1 genome annotation [52]. The genes located immediately downstream to the PUMA3 CSS locus are shown in bold. ECF, extracytoplasmic function; HUU, hypothetical, unclassified, unknown; TPS, two partner secretion.