Fig. 2.

Pedigree of a Korean family with cystic fibrosis. A heterozygous Q98R mutation is found in the father, brother, and the proband, and another heterozygous Q220X mutation is found in the mother and the proband. Squares indicate males, circles indicate females, and an arrow indicates the proband. Open symbols with or without central dot indicate carriers and an unaffected family member, respectively, and a darkened symbol indicates an affected family member.