TABLE 4.
Significant variables in final multivariable model predicting receipt of PMRT among those for whom it is not recommended
| OR | 95% CI | P-value | |
|---|---|---|---|
| Age | 0.048 | ||
| 50 years or older | 1.00 | ||
| Under 50 | 2.28 | 1.01–5.16 | |
| Education level | 0.001 | ||
| No college | 1.00 | ||
| At least some college | 3.49 | 1.54–7.92 | |
| Missing | 0.84 | 0.30–2.38 | |
| Tumor size | 0.0002 | ||
| Less than or equal to 2 cm | 1.00 | ||
| 2–5 cm | 3.15 | 1.72–5.80 | |
| Number of positive axillary lymph nodes | <.0001 | ||
| 0 | 1.00 | ||
| 1 | 3.88 | 1.47–10.23 | |
| 2 | 13.22 | 5.15–33.94 | |
| 3 | 15.37 | 5.15–45.86 | |
| Estrogen receptor status | 0.002 | ||
| Positive/unknown | 1.00 | ||
| Negative | 2.96 | 1.47–5.97 | |
| Histology | 0.005 | ||
| Ductal | 1.00 | ||
| All others | 2.72 | 1.36–5.47 | |
| Early reconstruction | 0.019 | ||
| Yes | 1.00 | ||
| No | 2.44 | 1.16–5.11 | |
| NCCN site | 0.026 | ||
| Site 8 | 1.00 | ||
| Site 1 | 5.75 | 0.99–33.38 | |
| Site 2 | 2.71 | 0.52–13.96 | |
| Site 3 | 8.29 | 1.59–43.19 | |
| Site 4 | 1.04 | 0.18–5.98 | |
| Site 5 | 3.73 | 0.71–19.46 | |
| Site 6 | 4.51 | 0.70–28.89 | |
| Site 7 | 2.53 | 0.47–13.49 | |
*
all patients in this cohort had negative surgical margins by definition