Table 2.
Pharmacokinetics of Aliskiren
| Parameter | Measure |
|---|---|
| Absorption | Poor (3%) |
| Distribution | 49.5% protein binding |
| Metabolism | Cytochrome P450 (CYP 3A4) |
| Elimination | Urine, feces |
| Time to peak concentration | 1–3 hours |
| Elimination half-life | 24 hours |
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