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. Author manuscript; available in PMC: 2009 Aug 21.
Published in final edited form as: Biochemistry. 2008 Jun 13;47(27):7147–7157. doi: 10.1021/bi800375m

Table 3.

Differential Thermodynamic Profiles for Pairs of Dodecamer Duplexes

[NaCl] (mM) ΔΔHcal (kcal/mol) Δ(TΔScal) (kcal/mol) ΔΔG°20 (kcal/mol) ΔΔnNa+ (mol of Na+/mol)
Substitution of dG with 7-Deaza-dG in DDD (DDDZ10 minus DDD)
10 10.0 9.2 0.8 0.6
100 21.8 17 4.8 0.5
Incorporation of Z3dU into DDD (DDD2+ minus DDD)
10 48.0 44.4 3.6 0.8
100 49.5 41.9 7.6 0.6
Incorporation of Z3dU into DDDZ10 (DDD2+Z10 minus DDDZ10)
10 31.7 29.3 2.4 0.5
100 17.5 15.8 1.7 0.2