TABLE I.

Details of the SNPs and Microsatellites Analyzed^a

Pathway	Gene	Base change	dbSNP reference	Amino acid change	Method
BER	ADPRT	T → C	rs17853760	Val762Ala	Cottet et al. [2000]b
	APEX	T → G	rs17858508	Asp148Glu	Hu et al. [2001]
	hOGG1	C → G	rs1052133	Ser326Cys	Wikman et al. [2000]c
	hOGG1	G → A	n/a	Arg46Gln	Wikman et al. [2000]
	XRCC1	G→A	rs25487	Arg399Gln	Lunn et al. [1999]
	XRCC1	C → T	rs1799782	Arg194Trp	Lunn et al. [1999]
	XRCC1	G → A	rs25489	Arg280His	Lunn et al. [1999]
	XRCC1	Microsatellite	—	Noncoding	Wilding et al. [2005]
NHEJ	XRCC4	T → C	rs28360135	Ile134Thr	Relton et al. [2004]
	XRCC4	G → T	rs1056503	Ser307Ser	See text
	XRCC5	Microsatellite	—	Noncoding	Wilding et al. [2005]
HRR	XRCC2	C → T	rs17856704	Pro36Ser	See text
	XRCC3	C → T	rs861539	Thr241Met	Shen et al. [1998]
	XRCC3	Microsatellite	—	Noncoding	Wilding et al. [2005]
NER	XPD	G → A	rs1799793	Asp312Asn	Spitz et al. [2001]
	XPD	A → C	rs13181	Lys751Gln	Spitz et al. [2001]

^aReferences to primers and methods are given. Minor modifications to published primers are detailed in the footnotes below. Novel primer sequences are given in the text.

^bReverse primer = Pex 19 of [Cottet et al. 2000]. Forward primer ADPRTT2444CF 5′-CAC CAT GAT ACC TAA GTC GG-3′.

^cPrimers with 5′ EcoRI site removed. Forward primer with additional 3′GGCT.