TABLE I.
CHARACTERISTICS OF CANCER PATIENTS BY CANCER SITE AND DIAGNOSTIC AGE-GROUP
| Cancer site1 | Pediatric (0–14 yrs)2 |
Adolescent (15–19 yrs) |
Young adult (20–34 yrs) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Males |
Females |
Males |
Females |
Males |
Females |
|||||||
| Patients | Proportion (%) | Patients | Proportion (%) | Patients | Proportion (%) | Patients | Proportion (%) | Patients | Proportion (%) | Patients | Proportion (%) | |
| Leukemia | 963 | 29.1 | 867 | 31.3 | 205 | 15.0 | 132 | 10.3 | 510 | 7.0 | 351 | 3.6 |
| Lymphomas | 397 | 12.0 | 218 | 7.9 | 327 | 23.9 | 273 | 21.2 | 1,465 | 20.0 | 1,013 | 10.4 |
| Hodgkin lymphoma | 120 | 3.6 | 86 | 3.1 | 212 | 15.5 | 211 | 16.4 | 877 | 12.0 | 645 | 6.6 |
| Non-Hodgkin lymphoma | 277 | 8.4 | 132 | 4.8 | 115 | 8.4 | 62 | 4.8 | 588 | 8.0 | 368 | 3.8 |
| Central nervous system | 829 | 25.1 | 691 | 25.0 | 243 | 17.8 | 188 | 14.6 | 933 | 12.8 | 927 | 9.5 |
| Sympathetic nervous system | 206 | 6.2 | 166 | 6.0 | 4 | 0.3 | 10 | 0.8 | 25 | 0.3 | 24 | 0.2 |
| Retinoblastoma | 106 | 3.2 | 81 | 2.9 | 0 | 0.0 | 0 | 0.0 | 1 | 0.0 | 0 | 0.0 |
| Renal tumors | 202 | 6.1 | 172 | 6.2 | 6 | 0.4 | 8 | 0.6 | 94 | 1.3 | 100 | 1.0 |
| Hepatic tumors | 35 | 1.1 | 18 | 0.7 | 11 | 0.8 | 10 | 0.8 | 40 | 0.5 | 51 | 0.5 |
| Malignant bone tumors | 124 | 3.8 | 99 | 3.6 | 136 | 9.9 | 87 | 6.8 | 231 | 3.2 | 138 | 1.4 |
| Soft-tissue sarcomas | 241 | 7.3 | 175 | 6.3 | 110 | 8.0 | 116 | 9.0 | 614 | 8.4 | 618 | 6.3 |
| Germ cell, trophoblastic and other gonadal neoplasms | 74 | 2.2 | 82 | 3.0 | 140 | 10.2 | 100 | 7.8 | 1,122 | 15.3 | 671 | 6.9 |
| Testes | 57 | 1.7 | 133 | 9.7 | 1,083 | 14.8 | ||||||
| Ovary | 46 | 1.7 | 89 | 6.9 | 578 | 5.9 | ||||||
| Other germ cell | 17 | 0.5 | 36 | 1.3 | 7 | 0.5 | 11 | 0.9 | 39 | 0.5 | 93 | 1.0 |
| Carcinomas and other malignant epithelial neoplasms3 | 100 | 3.0 | 167 | 6.0 | 164 | 12.0 | 346 | 26.9 | 2,170 | 29.7 | 5,722 | 58.7 |
| Thyroid | 15 | 0.5 | 39 | 1.4 | 27 | 2.0 | 141 | 11.0 | 296 | 4.0 | 1,206 | 12.4 |
| Cervix | 0 | 2 | 0.2 | 705 | 7.2 | |||||||
| Uterus | 0 | 1 | 0.1 | 69 | 0.7 | |||||||
| Breast | 0 | 1 | 1 | 0.1 | 6 | 0.5 | 5 | 0.1 | 1,697 | 17.4 | ||
| Stomach | 0 | 0 | 3 | 0.2 | 1 | 0.1 | 177 | 2.4 | 186 | 1.9 | ||
| Colon | 27 | 0.8 | 61 | 2.2 | 43 | 3.1 | 87 | 6.8 | 309 | 4.2 | 391 | 4.0 |
| Urinary bladder | 0 | 0.0 | 1 | 0.0 | 1 | 0.1 | 2 | 0.2 | 126 | 1.7 | 36 | 0.4 |
| Melanoma | 28 | 0.8 | 19 | 0.7 | 53 | 3.9 | 64 | 5.0 | 570 | 7.8 | 850 | 8.7 |
| Other carcinomas | 30 | 0.9 | 46 | 1.7 | 36 | 2.6 | 42 | 3.3 | 687 | 9.4 | 582 | 6.0 |
| Other and unspecified malignant neoplasms | 28 | 0.8 | 30 | 1.1 | 23 | 1.7 | 15 | 1.2 | 106 | 1.4 | 133 | 1.4 |
| Total | 3,305 | 100.0 | 2,766 | 100.0 | 1,369 | 100.0 | 1,285 | 100.0 | 7,311 | 100.0 | 9,748 | 100.0 |
1
The cancer site grouping used for pediatric and adolescent patients is based on the International Classification of Childhood Cancer.26
2
Diagnostic age-groups were defined according to age at diagnosis.
3
The carcinomas and other malignant neoplasms group is further divided into major subsites to account for the different malignancy patterns among young adults.