Table 6.
Model | Likelihood ratio chi-squared (p-value) a | Concordance/ generalized AUC b | Generalized R2c |
---|---|---|---|
Global cortical PiB only | 12.2 (<0.0001) | 0.75 | 0.27 |
Hippocampal W score only | 29.2 (<0.0001) | 0.84 | 0.55 |
Global PiB and W scored | 33.4 (<0.0001) | 0.86 | 0.60 |
Note: Due to skewness, global PiB was log transformed
Likelihood ratio test versus the null model
This can be interpreted as the probability of correctly identifying which is the more clinically impaired patient from a pair of patients having different diagnoses using only the imaging measure(s) in the model
This can be interpreted as the model likelihood divided by the likelihood from a saturated, or "perfect fitting" model, after adjusting for model complexity. In some sense, what proportion of the observed data is "explained" by the model
Significantly better than PiB only model (p<0.001) and hippocampal W score only model (p=0.040) by likelihood ratio test