. Author manuscript; available in PMC: 2009 Aug 21.

Published in final edited form as: Am Heart J. 2007 Oct;154(4):751–758. doi: 10.1016/j.ahj.2007.06.030

Table 5.

Regression models for MMP-1/MMP-3 combined genotypes in association with CAD vs. No-CAD (excluding MI patients) with adjustment for (Model A): age, sex, and ethnicity, and (Model B): age, sex, ethnicity, cardiac risk factors (hypertension, hyperlipidemia, diabetes, smoking, family history), and hsCRP (i.e., Model A + cardiac risk factors + hsCRP).

Composite Genotypes for MMP-1/MMP-3	Model A	Model B
Composite Genotypes for MMP-1/MMP-3	OR (95% CI), p-value	OR (95% CI), p-value
2G2G/6A6A	1.0, -----	1.0, -----
2G1G/6A6A	1.16 (0.79, 1.71), 0.45	1.33 (0.88, 2.02), 0.18
1G1G/6A6A	1.06 (0.51, 2.22), 0.87	1.15 (0.51, 2.61), 0.74
2G2G/6A5A	1.26 (0.85, 1.88), 0.26	1.22 (0.80, 1.87), 0.35
2G1G/6A5A	1.29 (0.96, 1.75), 0.10	1.26 (0.92, 1.74), 0.16
1G1G/6A5A	0.92 (0.64, 1.35), 0.68	0.90 (0.60, 1.34), 0.60
2G2G/6A5A	0.71 (0.31, 1.62), 0.42	0.70 (0.29, 1.70), 0.43
2G1G/6A5A	1.44 (0.97, 2.13), 0.07	1.46 (0.96, 2.22), 0.08
1G1G/6A5A	1.21 (0.85, 1.71), 0.29	1.21 (0.83, 1.75), 0.32