Table 2.

Left Ventricular Area at Risk

	Body Weight (g)	LV (g)	AAR (g)	AAR/LV (%)
CON	2367±310	3.35±0.29	1.41±0.18	42±5
APC	2534±422	3.07±0.39	1.09±0.11	36±5
IPC	2555±211	3.16±0.59	1.16±0.41	36±9
GELD	2504±217	3.14±0.36	1.11±0.16	36±7
APC + GELD	2210±97	3.28±0.32	1.44±0.23	44±4
IPC + GELD	2500±120	3.60±0.51	1.36±0.38	37±8
RAD	2185±57	3.12±0.25	1.39±0.15	44±3
APC + RAD	2160±106	3.22±0.29	1.32±0.23	41±5
IPC + RAD	2569±169†	3.80±0.49	1.46±0.25	38.5±4
L-NAME	2749±147*	3.14±0.66	1.24±0.41	39±8
APC + L-NAME	2288±113†	3.43±0.35	1.37±0.23	40±5
IPC + L-NAME	2238±169†	3.15±0.18	1.11±0.23	35±6

Data are mean±SD, n=8 per group.

^*P<0.05 vs Control;

^†P<0.05 vs corresponding drug alone (GELD, RAD, L-NAME).

Abbreviations: AAR = area at risk ; APC = anesthetic preconditioning (isoflurane, 1 minimal alveolar concentration); CON= control ; GELD = geldanamycin ; IPC = ischemic preconditioning ; L-NAME = N-Nitro-L-arginine methyl ester ; LV = left ventricle ; RAD = radicicol.