Table 2.

Expression of HDP Genes in Oral and Airway Epithelium

Oral Cavity
Peptide	Site of Expression	Regulation	Stimulant
hBD-1	Gingival epithelium	Inducible	P. gingivalis
hBD-2	Salivary glands, epithelium	Inducible	F. nucleatum, A. actinomycetemcomitans, IL-1β
hBD-3	Keratinocytes	Inducible	F. nucleatum, A. actinomycetemcomitans
LL-37	Gingival Epithelium	Inducible	Vitamin D
	Neutrophils	Constitutive	-
Histatins	Salivary glands	Constitutive	-
Airway
Peptide	Site of Expression	Regulation	Stimulant
hBD-1	Ciliated epithelium	Constitutive	-
	Plasmacytoid DCs	Inducible	Enveloped viruses
hBD-2	Ciliated epithelium	Inducible	Bacteria, TLR agonists, cytokines
hBD-3	Ciliated epithelium	Inducible	Bacteria, TLR agonists, cytokines
LL-37	Ciliated epithelium	Inducible	Vitamin D
	Neutrophils	Constitutive	-