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. Author manuscript; available in PMC: 2009 Aug 21.
Published in final edited form as: Neuroimage. 2008 Nov 27;47(Suppl 2):T27–T35. doi: 10.1016/j.neuroimage.2008.11.012

Fig. 4.

Fig. 4

MRI correlation with histology in NHP with right corona radiata AAV1-GFP RCD. (A) T1-weighted coronal MR image of NHP brain with right corona radiata convection. GDL extends within the white matter tracts and, on this image, does not enter the adjacent head of caudate or overlying cortex. No leakage is noted in the subarachnoid space. (B) Histologic coronal brain section of animal depicted in A, showing GFP staining within the corona radiata (cr), with sparing of the corpus callosum (cc), overlying cortex, and adjacent head of caudate (Cd). (C) Low magnification view of specific GFP staining in the convected corona radiata. White matter tracts are easily seen, interspersed with positively stained nuclei. Scale-bar=0.25 mm. (D) High magnification view of boxed inset in C, showing positively stained astrocytic and oligodendrocytic nuclei. Scale-bar=0.10 mm.