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. 2002 Oct;8(10):1138–1144. doi: 10.3201/eid0810.020331

Table 5. Predictors of discontinued Therapy (n=45) compared with full adherence (n=98), Washington, D.C., 2001a.

Predictor covariates Adjusted, OR (95% CI) p value
Age 18-44 y 6.7 (2.6 to 17.3) <0.05
Perceived riskb High 0.1 (0.01 to 0.8) <0.05
Some 0.4 (0.1 to 3.0) n.s.
None ref -
Adverse effectsc A lot 20.4 (3.0 to 140.1) <0.05
Some 1.7 (0.6 to 5.1) n.s.
Not at all ref -
Physical signs of stressd 5-11 signs 0.02 (0.003 to 0.2) <0.05
1-4 signs 0.3 (0.1 to 1.1) n.s.
0 signs Ref -
Anxietye Yes 3.5 (1.1 to 10.9) <0.05

aOR, odds ratio; 95% CI, 95% confidence interval; n.s., not statistically significant; ref, referent.
bPerceived risk of breathing in B. anthracis spores during exposure period October 12-21, 2001.
cReported how much side effects affected their life.
dPhysical signs of stress included fatigue, headaches, chest pain, rapid heartbeat, unplanned changes in weight, less or difficulty sleeping, muscle tremors or twitches, difficulty or rapid breathing, elevated blood pressure, nausea or vomiting, and dizziness or lightheadedness.
eReported they experienced anxiety since anthrax events started.  Anxiety was one of 22 listed symptoms of stress on our questionnaire.