TABLE 3.

Body Weights and Organ Weight Ratios (g) for Pups Born to Dams Exposed PCBs ± MeHg during Gestation and Lactation¹

Exposure Group PCB/MeHg	Birth Weight (PND 0)	Weaning Weight (PND 21)	Brain:Body Weight Ratio	Liver:Body Weight Ratio	Thymus:Body Weight Ratio
0 mg / 0 ppm (Control; 9 litters)
MALE	6.40 ± 0.11	46.02 ± 2.03BC	0.0322 ± 0.0017	0.0370 ± 0.0007ABCD	0.0042 ± 0.0002ABCD
FEMALE	6.11 ± 0.10	43.39 ± 1.86BC	0.0332 ± 0.0010	0.0374 ± 0.0008ABCD	0.0049 ± 0.0004ABCD
1 mg / 0 ppm (8 litters)
MALE	6.50 ± 0.19	48.10 ± 1.26	0.0312 ± 0.0011	0.0474 ± 0.0010BD	0.0039 ± 0.0001
FEMALE	6.21 ± 0.18	46.54 ± 1.27	0.0325 ± 0.0012	0.0472 ± 0.0009BD	0.0041 ± 0.0002
3 mg / 0 ppm (8 litters)
MALE	5.94 ± 0.18	43.36 ± 1.24ABC	0.0335 ± 0.0010A	0.0601 ± 0.0013C	0.0037 ± 0.0001
FEMALE	5.91 ± 0.27	41.52 ± 1.02ABC	0.0335 ± 0.0010A	0.0604 ± 0.0008C	0.0041 ± 0.0001
0 mg / 1.5 ppm (8 litters)
MALE	6.51 ± 0.11	49.63 ± 1.15	0.0302 ± 0.0009	0.0383 ± 0.0003ABCD	0.0043 ± 0.0002D
FEMALE	6.11 ± 0.14	48.11 ± 1.42	0.0321 ± 0.0014	0.0371 ± 0.0005ABCD	0.0044 ± 0.0002D
0 mg/ 4.5 ppm (9 litters)
MALE	6.64 ± 0.26	46.26 ± 2.74BC	0.0334 ± 0.0017A	0.0361 ± 0.0009ABCD	0.0042 ± 0.0002ABCD
FEMALE	6.39 ± 0.20	43.31 ± 1.96BC	0.0335 ± 0.0015A	0.0367 ± 0.0007ABCD	0.0048 ± 0.0002ABCD
1 mg/ 1.5 ppm (10 litters)
MALE	6.79 ± 0.14	50.24 ± 1.47	0.0301 ± 0.0009	0.0482 ± 0.0013	0.0040 ± 0.0002
FEMALE	6.43 ± 0.16	48.59 ± 1.46	0.0311 ± 0.0009	0.0484 ± 0.0022	0.0039 ± 0.0001
3 mg / 4.5 ppm (9 litters)
MALE	6.27 ± 0.10	44.58 ± 1.45BC	0.0323 ± 0.0012	0.0609 ± 0.0011C	0.0035 ± 0.0002
FEMALE	6.03 ± 0.07	43.24 ± 1.49BC	0.0339 ± 0.0010	0.0632 ± 0.0013C	0.0037 ± 0.0002

¹Data calculated on litters included in behavioral study (≥7 pups); Means (± SEM). g=grams; PCB =Polychlorinated biphenyls; MeHg = Methylmercury

^AWeaning Weight: Significant difference from 1.0 mg/kg PCB group

^Bsignificant difference from 1.5 ppm MeHg group

^Csignificant difference from 1.0 mg/kg PCB + 1.5 ppm MeHg group (all p<0.05)

^ABrain:BW Ratio: Significant difference from 1.0 mg/kg PCB + 1.5 ppm MeHg group (p<0.05)

^ALiver:BW Ratio: Significant difference from 1.0 mg/kg PCB group

^Bsignificant difference from 3.0 mg/kg PCB group, significant difference from

^C1.5 ppm PCB + 4.5 ppm MeHg group

^DSignificant difference from 3.0 mg/kg PCB + 4.5 ppm MeHg group (all p<0.001)

^AThymus:BW Ratio: Significant difference from 1.0 mg/kg PCB group

^Bsignificant difference from 3.0 mg/kg PCB group, significant difference from

^C1.5 ppm PCB + 4.5 ppm MeHg group

^Dsignificant difference from 3.0 mg/kg PCB + 4.5 ppm MeHg group (all p<0.05)