TABLE 4.

Effects of AMPH Drug Challenge on Total Responses and Reinforcers Delivered Following Developmental PCB and/or MeHg Exposure

	Males		Females
	Total Responses	Reinforcers Delivered	Total Responses	Reinforcers Delivered
Control
0 mg/kg AMPH	318.36±33.70	147.67±11.28	316.22±35.48	109.06± 9.40
0.5 mg/kg AMPH	385.97±41.35	144.03±8.33	416.89±48.40	89.17±9.99
1.0 mg/kg AMPH	623.43±83.75	74.71±12.44	544.11±96.28	70.89±13.07
1 mg/kg PCB
0 mg/kg AMPH	403.44±30.08	122.50±18.41	305.06±20.92	125.81±12.92
0.5 mg/kg AMPH	446.50±42.78	106.63±13.44	353.50±34.39	101.75±10.30
1.0 mg/kg AMPH	591.38±53.66	79.75±9.82	493.19±76.44	70.31±7.18
3 mg/kg PCB
0 mg/kg AMPH	345.75±39.08	117.81±12.66	311.31±44.55	107.88±14.79
0.5 mg/kg AMPH	440.31±34.86	106.94±19.19	375.00±52.12	103.31±13.50
1.0 mg/kg AMPH	530.81±24.10	82.88±14.71	506.56±115.95	69.75±10.31
1.5 ppm MeHg
0 mg/kg AMPH	328.38±24.50	134.50±11.64	320.56±39.03	153.13±13.03
0.5 mg/kg AMPH	343.19±22.66	113.19±8.08	457.94±55.11	111.31±9.05
1.0 mg/kg AMPH	405.69±30.26	103.50±5.96	552.50±81.73	89.88±8.95
4.5 ppm MeHg
0 mg/kg AMPH	300.55±24.19	137.09±9.77	325.21±11.50	128.86±10.39
0.5 mg/kg AMPH	373.64±39.49	127.03±7.05	412.86±15.17	102.64±7.67
1.0 mg/kg AMPH	548.37±50.28	101.04±1 1.48	581.79±57.08	68.57±5.13
1 mg/kg PCB/1.5 ppm MeHg
0 mg/kg AMPH	363.05±41.24	146.25±9.54	335.15±22.07	133.00±11.25
0.5 mg/kg AMPH	338.75±24.61	137.50±9.86	406.60±27.28	110.75±10.15
1.0 mg/kg AMPH	469.80±41.32	104.15±11.57	512.60±49.68	81.75±13.43
3 mg/kg PCB/4.5 ppm MeHg
0 mg/kg AMPH	360.11±26.39	155.89±13.77	356.71±29.66	135.42±15.28
0.5 mg/kg AMPH	410.61±37.84	133.61±14.62	410.10±35.09	111.30±9.95
1.0 mg/kg AMPH	700.94±94.49	74.50±11.57	545.47±76.57	77.61±7.36

Note. Values reported as mean ± SEM.

PCB =Polychlorinated biphenyls; MeHg = Methylmercury; AMPH = Amphetamine