Table 1.
Aggression-related brain gene regulation in honey bees as a function of heredity, alarm pheromone exposure, and age
| Experiment | No. of genes | Raw P value |
|---|---|---|
| AHB/EHB Guard | ||
| Individual genotype (I) | 249 | <0.0015 |
| Colony genotype (C) | 494 | <0.0025 |
| I × C | 64 | <0.0005 |
| AHB/EHB Soldier | ||
| Individual genotype (I) | 538 | <0.0025 |
| Colony genotype (C) | 830 | <0.005 |
| I × C | 114 | <0.0055 |
| AHB/EHB Forager | ||
| Individual genotype (I) | 58 | <0.00025 |
| Colony genotype (C) | 346 | <0.0015 |
| I × C | 190 | <0.001 |
| Alarm pheromone | 437 | <0.0025 |
| Old/Young | 1396 | <0.0055 |
Number of genes differentially expressed in each experiment. A false discovery rate (FDR) adjusted P value <0.05 was used as the threshold to determine statistical significance. I, differences due to individual genotype (AHB/EHB); C, differences due to colony genotype. Gene lists are in Dataset S1. Results based on individual brain gene expression profiles for 230 bees, involving a total of 332 microarrays (178, 64, and 90 for AHB/EHB, alarm pheromone and young/old experiments, respectively). For AHB/EHB, n = 5 bees per behavioral group per colony, except in one AHB and one EHB colony where 4 soldiers were analyzed, n = 2 colonies each of AHB and EHB; for alarm pheromone, n = 10 bees per group per colony, n = 2 colonies; for young/old bees, n = 12 bees per group per colony, n = 3 colonies.