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Summary of efficiencies of transformation
Efficiencies of transformation by Myc, Jun, P3K, or Src are shown for each compound at the indicated concentrations.
| Compound | Myc | Jun | P3K | Src |
|---|---|---|---|---|
| NSC13728 (2.5 μM) | 0.07 ± 0.04 | 0.90 ± 0.06 | 1.03 ± 0.19 | 1.14 ± 0.10 |
| NSC13728 (5 μM) | 0.01 ± 0.01 | 1.08 ± 0.07 | 0.90 ± 0.05 | 1.18 ± 0.20 |
| NSC13728 (10 μM) | 0.01 ± 0.00 | 0.57 ± 0.13 | 0.96 ± 0.20 | 0.78 ± 0.11 |
| 10058-F4 (7.5 μM) | 0.61 ± 0.11 | N.T. | N.T. | 0.95 ± 0.07 |
P3K, phosphoinositide 3-kinase; N.T., no transformation.
