Fig. 5.

Recombinant human ChM-I inhibited TrHBMEC tube formation in matrigel. Recombinant human ChM-I mature protein inhibited TrHBMEC tube formation in a dose-dependent manner (A-C). Arrows indicate the tube structures. Data represent similar results from three independent experiments. Total tube length per field was measured by image processing and analysis software. ^*, p < 0.05 is considered significant compared with untreated control. ^**, p < 0.05 is considered significant compared with untreated control and 1 μg/ml ChM-I treatment (D).