Table 1.
Morpholino and DNA sequences.
| sequence | abbreviation |
|---|---|
| 5' NH2-TTT TAA ATT CTG CAA GTG AT-CO(CH2)3SS(CH2)3CONH2 3' A | PM1 |
| Morpholino retinoblastoma RB1 marker probe; used for hybridization studies | |
| 5' NH2-TTT TAA ATT CTG CAA GTG AT-(CH2)3SS(CH2)3OH 3' | PD1 |
| DNA probe; same sequence as PM1 | |
| 5' TTT TTT TCC TTC CTT TTT TT-CO(CH2)3SS(CH2)3CONH2 3' A | PM2 |
| Morpholino probe; used for subrared reflection-absorption spectroscopy (IRRAS) studies | |
| 5' ATC ACT TGC AGA ATT TAA 3' | TD1 |
| DNA target; complementary to PM1 and PD1 | |
| 5' AAA AAA AGG AAG GAA AAA 3' | TD2 |
| DNA target; noncomplementary hybridization control |
A
The Morpholino PM1 and PM2 molecular structures are (m = 19):