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Phenotype and mtDNA genotype of transmitochondrial cybrid cell lines used in this study
| Cybrid cell line | Nuclear background | mtDNA mutation (gene) | Respiratory defect |
|---|---|---|---|
| Cy1‐I | ES‐I | 9821A del Mttr | Non‐pathogenic |
| Cy2‐I | ES‐I | 6589T>C Mtco1 | Mild |
| Cy2‐VI | ES‐VI | 6589T>C Mtco1 | Mild |
| Cy3‐I | ES‐I | 13887C ins Mtnd6 | Severe |
| 12273G>A Mtnd5 |
