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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: J Biol Inorg Chem. 2009 Apr 7;14(6):873–881. doi: 10.1007/s00775-009-0499-3

Figure 5. Reversal of TFO cross-linking with cyanide treatment.

Figure 5

The cross-linked product between the pyrimidine strand of the Pol DNA duplex and platinated N4-(aminopentyl)C-TFO was isolated from a gel and treated with either water or 200 mM sodium cyanide. The samples were then run on a 20% denaturing polyacrylamide gel, shown here.