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. Author manuscript; available in PMC: 2009 Aug 23.
Published in final edited form as: Cancer Cell. 2006 Dec;10(6):515–527. doi: 10.1016/j.ccr.2006.10.008

Figure 5. A functional model to investigate lead candidate therapeutic targets.

Figure 5

Gene expression and copy number for the 66 candidate therapeutic genes in the 51 breast cancer cell lines. Genes were selected for their overexpression and association with outcome in human breast tumors (Chin et al., 2006). High gene expression (≥2-fold over mean gene expression for all the samples) is shown in red, and high-level amplification (≥0.9 Log2 ratio) is shown in yellow for each cell line. Genes that have high expression and gene copy number are shown in blue. Gene HUGO names are shown to the right, and the corresponding BAC clone ID and chromosome are shown to the left.