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. 2009 Sep 1;4(9):e6879. doi: 10.1371/journal.pone.0006879

Figure 1. Nemosis response in different fibroblast populations.

Figure 1

Fibroblasts were grown as spheroids or monolayer for the time indicated. (A) FB-43 spheroids started to produce COX-2 after 48 hours and no α-SMA was produced, whereas CAF-43 cells (B) did not induce COX-2 but expressed α-SMA. Both FB-74 (C) and CAF-74 (D) produced α-SMA, but COX-2 was only induced in CAF-74 spheroids. All fibroblasts types expressed equal amounts of vimentin. (E) All UT-SCC cells expressed COX-2, but only 74A and 74B showed induced p53 levels.