Table 2. Prenatal growth retardation in Nipbl+/− embryos.

Genotype	E17.5 Body weight (g)			E17.5 Placental weight (g)			E18.5 Body weight (g)
	Mean	S.D.	N	Mean	S.D.	N	Mean	S.D.	N
+/+	1.02	0.096	30	0.115	0.015	23	1.27	0.076	7
Nipbl+/−	0.80*	0.115	23	0.112†	0.024	17	1.00*	0.082	7

Embryos were obtained at the indicated times from crosses of N₀ Nipbl+/− males and CD-1 females. Reduction in weight of 18–19% in mutant embryos is apparent at both ages, without a significant difference in placental weight.

*: P<0.001.

†: P = 0.64, by Student's t-test.