Skip to main content
. Author manuscript; available in PMC: 2009 Aug 24.
Published in final edited form as: J Infect Dis. 2008 Aug 15;198(4):516–524. doi: 10.1086/590117

Figure 1.

Figure 1

Dengue virus serotype 2 (DENV2) infection enhancement in diluted maternal plasma. A, n-Fold enhancement of infection of K562 cells by DENV2 (unbroken lines) after preincubation with dilutions of maternal plasma (n = 27), compared with plasma control samples (dashed lines) from flavivirus-naive individuals (n = 2), which did not enhance DENV2 infection at any dilution. B, Correlation, for each mother-infant pair, between the titer of maternal plasma that resulted in maximum DENV2-infection enhancement in K562 cells (from panel A) and the age of the infant when the pair presented to hospital with dengue caused by DENV2. There was a negative correlation between antibody-dependent enhancement of infection and the age of the infant (Spearman’s r = -0.39; P = .04).