Figure 6.

Brain-derived neurotrophic factor (BDNF) release by leucocytes in vitro. Monocyte-enriched human peripheral blood mononuclear cells of n = 22 healthy volunteers were stimulated with tumour necrosis factor α (TNFα, 50 ng/ml) for 24 h. Shown are BDNF concentrations (mean (SD)) in supernatants of wells containing fluticasone propionate (10⁻⁷ M), salmeterol xinafoate (10⁻⁷ M) and both fluticasone propionate (10⁻⁷ M) and salmeterol xinafoate (10⁻⁷ M), as compared with BDNF concentrations in the medium control.