Figure 1. Genetic mapping of H-2^k-linked MCMV resistance in chromosome 17 recombinant congenic strains.

A panel of seventeen recombinant congenic mouse lines (Table II) was generated and genotyped with genetic markers (Table I) to pinpoint chromosome 17 crossover sites. A. A chromosome 17 physical map between D17Mit16 and D17Mit10 (based on C57BL/6 genome, Build 37) is shown with a reference scale in megabases (Mb) included below. Also depicted are seven informative recombinant chromosome haplotypes with C57L- (light gray) or MA/My- (dark gray) derived intervals based on genetic analysis of the new mouse lines. B. A refined haplotype map for the critical genetic region based on genotype analysis of the four most informative intra-H-2 recombinant lines. SNP (∆) and SSLP (▲) genetic marker positions are indicated.