Figure 12.

Effect of genotype of sisters of on metabolic activity in a social behavior network in female wildtype (WT) and estrogen receptor a knockout (KO) mice. Groups are presented according to the type of sibling with which the WT (top row) or KO female (middle row) was raised with ♀KO or ♀WT sisters, respectively. The limbic landscape map on the upper right represents the difference in ♀WT raised with ♀KO sister. Below that is the complement, that is, the effect of a WT sister on the metabolic activity in ♀KO females. The bottom row indicates genotype differences between ♀WT and ♀KO females raised in same-sex, same-genotype litters. Right column is the effect of having a sister having the opposite genotype. Other details as in Figure 8.