Table 1. Demographical and clinical data of age-related macular degeneration patients and controls.
| Factors | AMD | Control | p-value |
|---|---|---|---|
| Age |
75.8±9.07 |
73.6±6.80 |
0.1682 |
| Gender (male/female) |
21/22 |
39940 |
0.7507 |
| Prior smoking |
24/43 (55.8%) |
3/12 (25.0%) |
0.1011 |
| Cancer history |
4/43 (9.3%) |
1/12 (9.1%) |
1 |
| Coronary heart disease | 11/43 (25.6%) | 2/12 (16.7%) | 0.7079 |
In both AMD and the controls, some of the individuals had a history of smoking, cancer and coronary artery disease, factors that may influence the melatonin level. Statistical significance of difference in the percentage or mean of these factors between AMD and the controls was analyzed by student’s t-test or Fischer’s exact test, respectively. There was no statistically significant difference in these factors between AMD patients and the controls.