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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Dev Dyn. 2009 Apr;238(4):875–886. doi: 10.1002/dvdy.21910

Fig. 7.

Fig. 7

foxd3 loss-of-function partially rescues melanophores from apoptosis in kitw34 larvae. A) 3dpf kitw34 larvae analyzed by TUNEL assay. Examples of posterior trunk melanophores positive for TUNEL signal are marked with white arrowheads. B) Brightfield image of larvae shown in A. TUNEL positive melanophores (black arrowheads) are distinct in size and shape. C) Line graph indicating the total number of TUNEL positive melanophores found in the dorsal stripe of uninjected or foxd3 MO injected kitw34 larvae quantified at 3, 4 and 5 dpf. There is a significant decrease in TUNEL positive melanophores at 3 dpf with foxd3 loss-of-function. (control n=45 fish, 649 TUNEL+ cells; foxd3MO n=64 fish, 493 TUNEL+ cells; *, p<0.001 by Bonferroni posttest at 3dpf).