Table 3.

Contraindications and Adverse Effects Associated with Phentermine (Adipex-P)

Contraindications Advanced arteriosclerosis Symptomatic cardiovascular disease Moderate to severe hypertension (stage II or III) Hyperthyroidism Glaucoma History of drug abuse Concomitant monoamine oxidase (MAO) inhibitor use or within 14 days of phentermine use Age younger than 16 years Hypersensitivity to sympathomimetic amines or any component of the formulation Adverse effects Exacerbation of symptoms of behavior and thought disorder in psychotic patients Increased systolic and diastolic blood pressure Tachycardia and palpitations Euphoria Insomnia and restlessness Dry mouth Diarrhea Impotence or changes in libido Tremor

From Adipex-P package insert, Teva, 2005.⁸