Table 3.
Allele and genotype distribution among asthmatic and controls.
| Asthma risk |
|||||
|---|---|---|---|---|---|
| Gene | Genotype | Asthmatic patients | Healthy controls | OR (95% CI)† | P-value |
| LIG4 (rs1805388) | G | 717 (84·2%) | 1068 (84·9%) | 0·95 (0·74–1·21) | 0·68 |
| A | 135 (15·8%) | 192 (15·2%) | |||
| GG | 302 (70·9%) | 450 (71·4%) | |||
| GA | 113 (26·5%) | 168 (26·7%) | |||
| AA | 11 (2·6%) | 12 (1·9%) | |||
| Total Genotyped | 426 | 630 | |||
| TNFSF13B (rs10508198) | G | 702 (82·8%) | 1058 (83·7%) | 0·93 (0·73–1·18) | 0·93 |
| C | 146 (17·2%) | 206 (16·3%) | |||
| GG | 290 (68·4%) | 440 (69·6%) | |||
| GC | 122 (28·8%) | 178 (28·2%) | |||
| CC | 12 (2·8%) | 14 (2·2%) | |||
| Total Genotyped | 424 | 632 | |||
| IRS2 (rs2289046) | T | 573 (67·3%) | 852 (67·7%) | 0·98 (0·82–1·18) | 0·88 |
| C | 279 (32·7%) | 406 (32·3%) | |||
| TT | 196 (46·0%) | 296 (47·1%) | |||
| TC | 181 (42·5%) | 260 (41·3%) | |||
| CC | 49 (11·5%) | 73 (11·6%) | |||
| Total Genotyped | 426 | 629 |
†
Logistic regression (age- and sex-adjusted); CI, confidence interval; OR, odds ratio.