Table 4.
Associations of hormones and regional fat mass with markers of cardiovascular risk
hsCRPa
|
TNF-α receptor 1
|
TNF-α receptor 2
|
E-selectin
|
sICAM-1
|
IL-6a
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
r | P | r | P | r | P | r | P | r | P | r | P | |
Peak GHa | ||||||||||||
Obese | −0.75 | 0.003 | −0.78 | 0.002 | −0.53 | 0.04 | −0.44 | NS | −0.74 | 0.004 | −0.37 | NS |
All | −0.46 | 0.01 | −0.58 | 0.001 | −0.60 | 0.0007 | −0.41 | 0.03 | −0.62 | 0.0005 | −0.23 | NS |
GH AUCa | ||||||||||||
Obese | −0.71 | 0.004 | −0.46 | 0.09 | −0.19 | NS | −0.23 | NS | −0.74 | 0.004 | −0.52 | 0.05 |
All | −0.45 | 0.02 | −0.41 | 0.03 | −0.43 | 0.02 | −0.33 | 0.08 | −0.61 | 0.0005 | −0.30 | NS |
IGF-I | ||||||||||||
Obese | −0.64 | 0.01 | −0.80 | 0.0004 | −0.61 | 0.02 | −0.36 | NS | −0.62 | 0.01 | −0.35 | NS |
All | −0.23 | NS | −0.32 | 0.08 | −0.23 | NS | −0.09 | NS | −0.30 | 0.10 | −0.08 | NS |
Adiponectin | ||||||||||||
Obese | −0.75 | 0.003 | −0.45 | 0.09 | −0.10 | NS | 0.13 | NS | −0.18 | NS | −0.86 | <0.0001 |
All | −0.39 | 0.03 | −0.37 | 0.04 | −0.15 | NS | −0.21 | NS | −0.20 | NS | −0.39 | 0.03 |
UFC | ||||||||||||
Obese | 0.42 | NS | −0.05 | NS | −0.30 | NS | −0.19 | NS | 0.25 | NS | 0.51 | 0.05 |
All | 0.50 | 0.005 | 0.18 | NS | 0.17 | NS | −0.02 | NS | 0.21 | NS | 0.55 | 0.002 |
Peak GH/UFC | ||||||||||||
Obese | −0.86 | 0.0002 | −0.61 | 0.03 | −0.43 | NS | −0.22 | NS | −0.79 | 0.001 | −0.43 | NS |
All | −0.57 | 0.002 | −0.44 | 0.02 | −0.50 | 0.007 | −0.22 | NS | −0.53 | 0.004 | −0.32 | 0.09 |
Leptin | ||||||||||||
Obese | 0.75 | 0.001 | 0.69 | 0.0005 | 0.58 | 0.02 | −0.16 | NS | 0.09 | NS | 0.61 | 0.02 |
All | 0.75 | <0.0001 | 0.76 | <0.0001 | 0.72 | <0.0001 | 0.32 | 0.08 | 0.50 | 0.005 | 0.60 | 0.0005 |
Total fat | ||||||||||||
Obese | 0.81 | 0.0003 | 0.54 | 0.04 | 0.34 | NS | −0.25 | NS | 0.21 | NS | 0.69 | 0.005 |
All | 0.78 | <0.0001 | 0.69 | <0.0001 | 0.62 | 0.0003 | 0.23 | NS | 0.57 | 0.001 | 0.65 | 0.0001 |
SAT | ||||||||||||
Obese | 0.78 | 0.002 | 0.42 | NS | 0.25 | NS | −0.31 | NS | 0.09 | NS | 0.59 | 0.03 |
All | 0.74 | <0.0001 | 0.63 | 0.0003 | 0.58 | 0.001 | 0.25 | NS | 0.51 | 0.005 | 0.57 | 0.001 |
VAT | ||||||||||||
Obese | 0.63 | 0.02 | 0.50 | 0.08 | 0.30 | NS | 0.41 | NS | 0.59 | 0.03 | 0.13 | NS |
All | 0.61 | 0.0006 | 0.65 | 0.0002 | 0.55 | 0.003 | 0.52 | 0.005 | 0.68 | 0.0001 | 0.35 | 0.07 |
NS, Not significant.
After log conversion to approximate a normal distribution.