Effect of DAPT delivery method on the structure and phenotype of small intestine. Representative images of tissue sections from small intestines isolated from mice without any treatment(control), mice treated with 860ng DAPT delivered from alginate gel ((DAPT)gel), or 860ng DAPT injected intraperitoneally ((DAPT)ip), which were stained against Notch gene HES-1 expression (A, B, C), Ki67 expression (D, E, F), alcian blue staining for glycosaminoglycans (G, H, I), or hematoxylin and eosin staining (J, K, L). Scale bar, 100μm.