Table 5.
Adverse events related to treatment of myasthenia gravis with corticosteroids
Strategies for prevention | |
---|---|
Sodium/fluid retention | Sodium-restricted diet |
Obesity | Low-calorie, low-fat diet; exercise |
Potassium loss | Supplement as needed |
Hypertension | Monthly checks with treatment as necessary |
Impaired glucose tolerance | Monitor fasting blood glucose and treat if necessary |
Osteoporosis | Bisphosphonates, calcium plus vitamin D, bone-density measurements, female hormone replacement therapy |
Psychosis/anxiety | Anxiolytics, antidepressants, use minimum effective steroid dose |
Cataracts/glaucoma | At least yearly ophthalmological assessment |
Steroid myopathy | Exercise, high-protein diet |
Growth suppression (children) | Use minimum effective dose |
Peptic ulcer disease | Histamine H2 receptor antagonists, proton-pump inhibitors |