Table 3. Vesicle size and lipopeptide association of lipopeptide liposomes.

Vesicle size was determined by dynamic light scattering and the fraction of lipopeptide in the liposome pellet following ultracentrifugation was measured by A280 as described in the Methods. ND – not determined.

Formulation	Vesicle Diameter (nm)	Standard Deviation (nm)	%Association
Empty	214.9	2.2	0.00
N-MPR	185.6	3.7	24.18
N-MPR-PA	175.5	9.1	ND
N-MPR-DPG	218.5	4.4	100.00
N-MPR-PC	212.6	17.1	81.89
N-MPR-PE	118.5	9.6	ND
N-MPR-SM	193.7	2.5	ND
N-MPR-CL	241.1	6.5	92.07
N-MPR-CHOL	153.2	8.9	94.90
N-MPR-CHEMS	192.9	6.8	99.71
N-MPR-CHEMS (no liposome)	ND	ND	0.00
C-MPR	222.4	2.5	98.97
C-MPR-PA	213.4	1.3	ND
C-MPR-DPG	216.6	2.1	ND
C-MPR-PC	246.2	1.8	ND
C-MPR-CHOL	211.7	0.2	ND
C-MPR-CHEMS	220.7	9.0	100.00
NC-MPR	240.0	2.1	100.00
NC-MPR-DPG	235.7	1.1	ND
NC-MPR-CHEMS	249.5	5.7	100.00
CHEMS-NC-MPR	288.7	13.5	97.42
CHEMS-NC-MPR-CHEMS	225.9	9.6	95.24