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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Toxicon. 2009 Mar 25;54(5):575–582. doi: 10.1016/j.toxicon.2009.03.016

Table 1.

List of the 7 serotypes of the botulinum neurotoxin, including the cleavage site of the protein cleaved by each light chain of the serotype and which type of host they affect. VAMP (vesicle associated membrane protein) also known as synaptobrevin; SNAP-25 (synaptosomal associated protein).

Serotype Host Protein substrate Cleavage site
A Human SNAP-25 Gln197-Arg198
B Human VAMP Gln76-Phe77
C Animal SNAP-25, Syntaxin Arg198-Ala199
Lys253-Ala254
D Animals VAMP Lys59-Leu60
E Human, Fish SNAP-25 Arg180-Ile181
F Human VAMP Gln58-Lys59
G Human VAMP Ala81-Ala82