Table 3.
Baseline (pretreatment) integrated area under the concentration curve of gadolinium contrast at 90 (AUC 90) and 180 (AUC 180) s from the start of contrast enhancement
AUC 90 > 17.1 (n = 14) | AUC 90 ≤ 17.1 (n = 14) | P | AUC 180 > 34.2 (n = 14) | AUC 180 ≤ 34.2 (n = 14) | P | |
Response rate | 8 (57.1%) | 4 (28.6%) | 0.13 | 7 (50%) | 5 (35.7%) | 0.44 |
Progression-free survival | 7.4 months | 6.8 months | 0.077 | 7.2 months | 7.3 months | 0.77 |
Hepatic progression-free survival | 11.5 months | 7.5 months | 0.28 | 11.5 months | 7.5 months | 0.18 |
Disease-specific survival | 35.1 months | 19.1 months | 0.019 | 35.1 months | 19.1 months | 0.002 |
Survival >18 months | 12 (85.7.3%) | 9 (64.3%) | 0.19 | 13 (92.9%) | 8 (57.1%) | 0.029 |
Survival >24 months | 10 (71.4%) | 5 (35.7%) | 0.058 | 10 (71.4%) | 5 (35.7%) | 0.058 |
Patients were stratified around the median values for both variables. Region of interest analyses were carried out. Units for AUC—mM·s.
AUC, area under the concentration curve.