Table 3.

Response to treatment and response duration (n = 29)

Clinical response (WHO criteria)	No. of patients	%	95% CI
CR	2	6.9	0.8–22.8
PR	2	6.9	0.8–22.8
SD	3	10.3	2.2–27.4
Progressive disease	20	69	49.2–84.7
Not assessable	2	6.9	0.8–22.8
Overall response (CR + PR)	4	13.8	5.5–30.6
Overall clinical benefit (CR + PR + SD)	7	24.1	10.3–43.5
Response duration
Median progression-free survival	2.6 months		2.0–4.2 months
Progression-free survival at 1 year	10.3%		2.6%–24.3%
Median overall survival	6.8 months		3.5–12.4 months
Overall survival at 1 year	30.6%		15.2%–47.7%

WHO, World Health Organisation; CI, confidence interval; CR, complete response; PR, partial response; SD, stable disease.