Figure 5.
Chemokine and cytokine response in mice. Homogenates of the lung and spleen of six mice each group were infected with 106 PFU of SC35 and SC35M; three animals for each time point (3 and 6 days p.i.) were assessed for chemokine and cytokine response as described in Materials and Methods. Positive signals yielded with antibodies against sTNFRI (A), IL-4 (B), IL-12 (C), and MCP-1 (D) 3 and 6 days p.i. are shown as arbitrary units (AU). Each bar is representative for three independent experiments. Error bars indicate SD of independent experiments.