Table 2.
Blood Parameters of Infected Mice
| Blood cell count | PBS | SC35
|
SC35 mol/L
|
||
|---|---|---|---|---|---|
| 3 days p.i. | 6 days p.i. | 3 days p.i. | 6 days p.i. | ||
| WBC (103/mm3) | 6.4 | 6.7 | 9.2 | 5.0 | 3.8 |
| ±0.7 | ±3.0 | ±0.9 | ±0.1 | ±1.2 | |
| RBC (106/mm3) | 7.9 | 9.1 | 8.5 | 10.4 | 5.8 |
| ±0.8 | ±1.3 | ±0.9 | ±0.3 | ±1.1 | |
| HGB (g/dl) | 14.1 | 16.3 | 14.5 | 17.6 | 9.6 |
| ±1.1 | ±1.8 | ±1.7 | ±0.3 | ±1.7 | |
| HCT (%) | 44.4 | 45.4 | 47.1 | 56.2 | 30.5 |
| ±3.8 | ±6.4 | ±5.3 | ±1.6 | ±6.0 | |
| PLT (103/mm3) | 1161 | 447 | 782 | 1348 | 446 |
| ±157 | ±179 | ±141 | ±68 | ±234 | |
| LYM (103/mm3) | 4.8 | 3.1 | 5.9 | 2.1 | 1.9 |
| ±0.6 | ±0.5 | ±0.4 | ±0.1 | ±0.7 | |
| MO (103/mm3) | 0.01 | 0.2 | 0.1 | 0.1 | 0.05 |
| ±0.0 | ±0.3 | ±0.0 | ±0.0 | ±0.1 | |
| GRA (103/mm3) | 1.6 | 3.9 | 3.3 | 2.8 | 1.9 |
| ±0.2 | ±0.4 | ±0.4 | ±0.3 | ±0.4 | |
Mice were infected with 106 PFU of SC35 and SC35M. Blood of three to five infected animals was collected 3 and 6 days p.i. by retroocular puncture and analyzed using an ABC blood counter for detection of white blood cells (WBC), red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), platelets (PLT), lymphocytes (LYM), monocytes (MO), and granulocytes (GRA). As a control, PBS-inoculated mice were used. SDs (±) are indicated underneath the bold measurements.