Table 1.
Reduced Serum Testosterone Levels in AROM+ Mice
| Age (weeks) | Testosterone (ng/ml)
|
Significance | |
|---|---|---|---|
| Wild-type | AROM+ | ||
| 5 | 8.54 ± 5.85 | 0.10 ± 0.06 | P = 0.0141 |
| 15 | 7.44 ± 9.48 | 0.66 ± 0.29 | P = 0.0216 |
| 26–36 | 7.50 ± 10.78 | 0.94 ± 0.69 | P = 0.0214 |
| 45–59 | 5.84 ± 8.18 | 3.07 ± 4.54 | NS |
Circulating serum testosterone levels in AROM+ mice were determined by RIA and were significantly reduced in AROM+ mice versus wild-type controls across all age groups, except at 45 to 59 weeks of age (n ≥10 for each age group).